science · 19 May 2009 · 15 years ago
death
Died 19 May 2009 at age 92 (born 4 Jun 1916).
Robert Francis Furchgott was an American pharmacologist who shared (with Louis J. Ignarro and Ferid Murad) the 1998 Nobel Prize in Physiology or Medicine for the discovery that nitric oxide (NO) acts as a signaling molecule in the cardiovascular system. Their combined work uncovered an entirely new mechanism by which blood vessels in the body relax and widen. Nitric oxide (NO), produced by one cell, acts by penetrating membranes and regulating the function of another cell. Nerves and hormones are well known as signal carriers, but this discovery was a totally new signaling principle in a biological system.